Sperm Capacitation and the Acrosome Reaction
نویسندگان
چکیده
منابع مشابه
Protein kinases in mammalian sperm capacitation and the acrosome reaction.
Binding to the zona pellucida of an egg stimulates the spermatozoon to undergo the acrosome reaction, a process that enables it to penetrate the egg. Before this binding, the spermatozoon undergoes a series of biochemical transformations in the female reproductive tract, collectively called capacitation. Only capacitated spermatozoa can bind to the zona pellucida and undergo the acrosome reacti...
متن کاملRole of tyrosine phosphorylation in sperm capacitation / acrosome reaction
Capacitation is an important physiological pre-requisite before the sperm cell can acrosome react and fertilize the oocyte. Recent reports from several laboratories have amply documented that the protein phosphorylation especially at tyrosine residues is one of the most important events that occur during capacitation. In this article, we have reviewed the data from our and other laboratories, a...
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s:2086:"Background: Cissampelos capensis, is commonly known by the Afrikaans name "dawidjies" and is the most important and best known medicinal plant of the family Menispermaceae used by the Khoisan and other rural people in the western regions of South Africa. Among numerous other ailments, it is taken to treat male fertility problems. The aim of this study was to investigate the effects of C...
متن کاملRegulation of sperm capacitation and the acrosome reaction by PIP2 and actin modulation
Actin polymerization and development of hyperactivated (HA) motility are two processes that take place during sperm capacitation. Actin polymerization occurs during capacitation and prior to the acrosome reaction, fast F-actin breakdown takes place. The increase in F-actin during capacitation depends upon inactivation of the actin severing protein, gelsolin, by its binding to phosphatydilinosit...
متن کاملRole and regulation of EGFR in actin remodeling in sperm capacitation and the acrosome reaction.
To bind and fertilize the egg, the spermatozoon should undergo few biochemical and motility changes in the female reproductive tract collectively called capacitation. The capacitated spermatozoon binds to the egg zona pellucida, and then undergoes the acrosome reaction (AR), which allows its penetration into the egg. The mechanisms regulating sperm capacitation and the AR are not completely und...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 1991
ISSN: 0077-8923,1749-6632
DOI: 10.1111/j.1749-6632.1991.tb27330.x